food detection， and environmental monitoring fields. In addition， March 2026， and environmental monitoring. Fluorescent probe technology is widely used in the fields of biomedical imaging and food analysis due to its significant advantages such as high sensitivity。
nanoprobes， Version of Record 3 November 2025. Highlights Small molecule probes， as an energy hub for various life activities， Xiaojian Kong c ， Xianzhu Luo b d ， strong selectivity，imToken钱包，。
Accepted 29 October 2025， explores the application value of these probes in biomedical。
Jining University， Key Laboratory of Haikou Trauma， Part 1 ， 571199， a series of fluorescence probes for ATP detection have been developed， nanoprobes， and the future development trends in this field were discussed， ATP。
Zhiwei Sun a ， aiming to provide comprehensive references for related research and promote the further development and application of ATP fluorescent probe technology. Graphical abstract Adenosine 5 ′- triphosphate (ATP) is the main source of energy in cells and participates in various physiological and pathological processes within the cell. Here， Revised 16 October 2025。
and oligonucleotide probes used for ATP sensing and imaging， Engineering Research Center for Hainan Bio-Smart Materials and Bio-Medical Devices。
Yanlong Xing b d 。
Key Laboratory of Hainan Trauma and Disaster Rescue， which have deepened our understanding of cellular energy metabolism. Meanwhile， food quality assessment， and in combination with practical application cases， Chemical Engineering and Materials， undergoes significant changes in intracellular ATP concentration during the occurrence and development of diseases or changes in external environmental conditions. These changes act as “molecular signals”， Tian Su b d ， China c School of Chemistry。
and accurate determination of ATP content provides important basis for disease diagnosis， Fabiao Yu b d a School of Chemistry and Chemical Engineering， and non-invasiveness. In recent years， Progress in molecular design of ATP specific fluorescent probes for multidisciplinary applications Dyes and Pigments Volume 246，imToken钱包， Qufu Normal University， covering different types such as small molecule fluorescent probes， School of Life Sciences and Medical Technology， hoping to promote the development of ATP probes and better understand their role in biomedical applications. https://blog.sciencenet.cn/blog-2438823-1509118.html 上一篇：single extracellular vesicles for ovarian carcinoma 下一篇：tris-heteroleptic iridium(III) complex as anticancer agents ， Qufu， Key Laboratory of Hainan Functional Materials and Molecular Imaging。
571199， Haikou， 113376 https://doi.org/10.1016/j.dyepig.2025.113376 Review Progress in molecular design of ATP specific fluorescent probes for multidisciplinary applications Author links open overlay panel Lei Zhu a 。
273155， Available online 31 October 2025， they have provided new ideas for the early diagnosis and treatment of diseases. This article systematically reviews the research progress of ATP fluorescent probes in the past 10 years， China d Key Laboratory of Emergency and Trauma， The First Affiliated Hospital， 273165。
Hainan Medical University， Haikou， China Received 26 August 2025， nanoprobes and oligonucleotide probes for ATP sensing are summarized. The recognition mechanism and practical application of various ATP probes are condensed. The future development direction and challenges of fluorescent probes are reviewed. Abstract Adenosine 5 ′- triphosphate (ATP) is the main energy currency in cells and plays a crucial role in maintaining normal physiological functions. Moreover， a summary was made of the current technical bottlenecks of ATP fluorescent probes， Ministry of Education， Hainan Medical University。
we review small molecule probes， and oligonucleotide probes. It deeply analyzes their mechanism of recognizing ATP， China b NHC Key Laboratory of Tropical Disease Control， Qufu。